There Were More Asymptomatic Infections In Guangzhou. The New Coronal Vaccine Has A Prominent Effect In Preventing Severe Diseases

? ? ? ? With the development of large-scale nucleic acid detection and screening, Guangzhou has basically grasped the transmission track of new coronavirus.

? ? ? ? According to the report of Guangzhou Municipal Health Commission on June 1, 10 newly confirmed cases were found in Guangzhou from 0:00 to 24:00 on May 31, 1 case was transferred from asymptomatic infection previously announced, and 1 case was newly imported from abroad. From 0:00 to 24:00 on May 31, 2021, 10 new cases of asymptomatic infection were added, including 2 cases in China and 8 cases imported from abroad. The 10 newly confirmed cases and 2 asymptomatic infection cases in the territory were actively investigated from close contacts and key population, and all of them were positive for the detection of new coronavirus nucleic acid, so they were transferred to Guangzhou Eighth People's Hospital for isolation treatment.

From 0:00 to 24:00 on May 30, 2021, 4 new confirmed cases were found in Guangzhou, 14 cases were transferred from asymptomatic infection cases previously announced, and 3 cases were newly imported confirmed cases. From 0:00 to 24:00 on May 30, 2021, two new cases of asymptomatic infection were imported from abroad.

? ? ? ? From the recent official data of the epidemic situation, it is worth noting that the number of asymptomatic infections in this round of epidemic situation is large, and there are also cases of asymptomatic infections turning into confirmed cases in the confirmed cases. Experts said that these may be related to vaccination and the characteristics of the virus strain, to a certain extent, it also greatly eased the pressure on the treatment end, the overall medical care was calm, and the anti epidemic situation was carried out smoothly.

On June 1, Chen Bin, deputy director of the Guangzhou Municipal Health Commission and spokesman, said in a reply to reporters' questions that the recent positive cases found in Guangzhou were closely related to the characteristics of the mutants found in India. The discovery of related cases is also the result of Guangzhou's faster and stronger prevention and control measures. At present, Guangzhou allows potential infected people to be diagnosed in a shorter period of time, even before the onset of the disease.

"Among the reported cases, 18 cases of asymptomatic infection turned into confirmed cases, which is the embodiment of effective screening in Guangzhou. Next, Guangzhou will dynamically update and compare the distribution of positive cases, study and judge the development trend of the epidemic situation, and adjust the prevention and control areas when appropriate. "

Liming, vice mayor of Guangzhou, said earlier that the virus causing the epidemic had the characteristics of short incubation period, fast transmission speed and high viral load, "according to the current situation, the transmission track of the virus is under our control."

Vaccination is an important way to deal with infectious diseases. People's vision

Comprehensive screening of asymptomatic infection: early detection and early treatment

In this round of epidemic transmission in Guangzhou, the number of asymptomatic infected people was the majority, which became one of the outstanding characteristics.

Guangzhou epidemic prevention and control headquarters decided to further expand the scope of nucleic acid detection for all staff from May 30, on the basis of continuing to organize nucleic acid screening in Liwan District, covering the whole area of Yuexiu District and Haizhu District, as well as the key areas of Tianhe District, Baiyun District and Panyu District.

On June 1, Chen Bin, deputy director of Guangzhou Municipal Health Commission and spokesman, said that the newly reported cases on May 31 showed two distribution characteristics: one was regional concentration. Like the previous cases, the new 12 cases are still concentrated in two key control areas, including 2 cases in Zhongnan street and 10 cases in BAIHEDONG street. The second is the phenomenon of family aggregation. Of the 12 cases, 10 cases involved 5 families.

Cai Weiping, chief expert of the infectious diseases center of the Eighth People's Hospital of Guangzhou, said that large-scale nucleic acid testing can more timely detect asymptomatic infections and help them to find and treat them early.

According to the definition of "new coronavirus pneumonia prevention and control program (Sixth Edition)", the "asymptomatic infector" of new coronavirus refers to those who have no clinical symptoms, and whose respiratory tract specimens are positive for new coronavirus etiology or serum specific IgM antibody.

In the "new coronavirus pneumonia case monitoring program (Third Edition)" released on January 28, 2020, the "asymptomatic infected person" is distinguished from suspected cases, confirmed cases and mild cases. If the nucleic acid test of new coronavirus is positive but no symptoms, it will not be included in the confirmed cases published every day.

According to Cai Weiping's analysis, several rounds of nucleic acid testing should be carried out in the middle risk areas with confirmed patients or asymptomatic infections; For the infected people have been to the site before the onset of the disease, also need to be as a key area of nucleic acid detection for screening; For places where there is no epidemic for the time being, the local residents also have the potential risk of intersecting with the track of the infected person in other regions.

"This round of testing in Guangzhou has screened out a number of infected people, which is very important for the prevention and control of the epidemic situation, because most asymptomatic infected people do not have symptoms such as fever, so they can not be found by themselves."

For the general population, nucleic acid screening can find out asymptomatic infections in time and block the spread of the virus; For asymptomatic infections, nucleic acid screening can help them get timely treatment after being found, and reduce the risk of becoming severe.

The Information Office of the State Council issued relevant regulations on the management of asymptomatic infected persons, requiring medical and health institutions at all levels and types to report asymptomatic infections through the Internet within 2 hours. After receiving the report of asymptomatic infection, the county (District) CDC should complete the case investigation within 24 hours, register the close contacts in time, and report the case investigation report through the infectious disease report management system in time.

Asymptomatic patients should be isolated for 14 days. In principle, they should be isolated for 14 days. If the nucleic acid test is negative, the isolation can be removed. If the nucleic acid test is still positive, the isolation should be continued. Close contacts of asymptomatic infections were also subjected to 14 days of isolation medical observation. If clinical symptoms appear during the centralized isolation medical observation, they should be transferred to the confirmed cases in time and transferred to the designated hospital for standardized treatment.

Liu Youning, former director of the Institute of respiratory diseases of the PLA, also said that during the isolation period, nucleic acid detection and further observation of whether there are symptoms can also be used to intervene with some antiviral drugs.

The effect of vaccination against severe diseases: influenza of new coronal epidemic

The mutant strain in India has the characteristics of high temperature resistance and strong transmission.

The local cases in Guangzhou have the same characteristic: the CT value of new coronavirus is particularly low. Cai Weiping said, "this is a semi quantitative data value. The lower the value, the higher the viral load on the patient, and the more active the virus is in the respiratory tract of the patient. In this group of patients, this value is generally low. "

Due to the high viral load, on the one hand, it has led to the enhancement of the transmission capacity of the virus, which has been fully illustrated by the current situation of anti epidemic. On the other hand, because of the high viral load, the patients' condition is progressing rapidly in the absence of antiviral drugs so far.

In the course of last year's anti epidemic, Guangzhou experts observed that the process of the disease from mild to severe was usually about 7-8 days. But this time, the progress of some patients is very fast, 2-3 days may occur significantly worse phenomenon.

However, in the face of this variant strain, the domestic new crown vaccine has shown a strong strength in the prevention of severe diseases.

At the 7th Annual Academic Meeting of the academic department of the Chinese Academy of Sciences on May 30, Gao Fu, academician of the Chinese Academy of Sciences and director of the China Center for Disease Control and prevention, said: "the new epidemic has become more and more influenza like. We may need to get vaccinated every year in the future, just like influenza and live with the new coronavirus for a long time." Gao Fu believes that due to the universal vaccination of the new crown vaccine, people have established a group immunity, but the main function of the vaccine at that time is not to prevent infection, but to prevent severe and death.

"The majority of asymptomatic infections are related to virus toxicity and host immune status (including vaccination)," Guo yabing, executive deputy director of Infectious Medicine and liver disease center of Southern Hospital of Southern Medical University, told reporters of 21st century economic news

Cai Weiping said that the results of clinical feedback showed that our vaccine had an outstanding effect in preventing severe diseases“ Some of them haven't completed the two injections of vaccination according to the prescribed process. But even so, with only one injection, we can see that they can produce antibodies quickly after infection

Vaccination is an important way to deal with infectious diseases. Cai Weiping said that the human body through the vaccine to produce antibodies, even if infected with the virus, can greatly reduce the probability of turning into severe and critical illness. However, if there is no vaccination, there is no need to queue up. It is recommended to make an appointment before vaccination.

Guangdong has been vigorously promoting vaccination for suitable population. Since the launch of the new coronapneumonia vaccination, Guangdong Province has been in the forefront of the country.

Among them, 428 inoculation sites (including large-scale inoculation sites) and 1998 inoculation units were set up in Guangzhou, with the highest daily inoculation amount of 510000 doses. As of May 27, Guangzhou had received 11.475852 doses of vaccination, with 8.671194 vaccinated, and 2993889 people completed the whole immunization program.

Subsequently, under the influence of the epidemic situation, the whole vaccination work was further accelerated. As of 16:00 on May 31, the city had received 13.136 million doses.

Delay of individual vaccine appointment in the whole city

On June 1, Zhang zhoubin, deputy director of Guangzhou Center for Disease Control and prevention, said in a press conference on June 1 that it was mainly considered from three aspects: manpower coordination, avoiding the risk of transmission caused by crowd gathering, and the effect of antibody onset time on epidemic prevention and control.

First, it is the most important thing to put an end to this unprecedented epidemic as soon as possible.

He said: "prevention and control take the initiative to upgrade, implement prevention and control before locking, expand the prevention and control strategy that takes the lead in screening, large-scale nucleic acid screening, screening of close and secondary secrets, tracking and transportation, and flow dispatching all need a large number of medical personnel to participate in order to ensure that prevention and control can be accelerated again, and the weight and quantity can be increased. A large number of medical staff are required to participate in the vaccination of large-scale population with new crown vaccine, so as to ensure the safety of vaccination. In order to avoid two line operations, we must concentrate our superior forces and engage in the epidemic prevention and control war to ensure that the epidemic situation can be controlled and exterminated in the shortest possible time. Then, we will adjust resources to push forward the vaccination work of new coronal vaccine

Second, in the current situation of prevention and control, reducing the concentration of people is one of the most important means to stop the spread of the epidemic. However, due to the impact of the epidemic situation, people's willingness to vaccinate is high, which leads to the gathering of people at the vaccination site, and there is a risk of cross infection.

Third, the antibody produced by vaccination needs a period of time. It does not mean that vaccination today will have protective effect tomorrow. Therefore, the recent vaccination is not very helpful to resist the current epidemic situation and prevent infection.

Based on the above reasons, personal appointment and social vaccination were suspended. However, group appointment and group vaccination for key industries and groups did not stop. In accordance with the principle of territorial management, the district level industry competent department shall apply to the district prevention and control command office for collective vaccination according to the actual vaccination situation of key industry posts in the jurisdiction, and assign special personnel to manage the personnel of the industry at the vaccination site, so as to ensure the implementation of various prevention and control measures and maintain a good on-site vaccination order.

As citizens, we may be concerned about whether not vaccinating the whole course on time will affect the effectiveness of vaccine protection or have adverse effects on the body.

Zhang zhoubin said: "the state currently recommends that the second dose of the new coronavirus inactivated vaccine be completed as soon as possible in eight weeks. It is hoped that we can complete the whole vaccination as soon as possible, so that the vaccine can play a role as soon as possible. The second dose over 8 weeks can also stimulate the body to produce effective protective antibody. At the same time, according to the national "technical guidelines for new coronavirus vaccination", citizens who fail to complete the second dose of vaccination according to the recommended time only need to follow-up the second dose of vaccine, and do not need to start the whole vaccination again. Therefore, as long as two doses of vaccination are completed, the protective effect of the vaccine will not be affected, and there will be no adverse effect on the body. "

In addition, it is not only the strong will of individual citizens, but also the need to establish a population immune barrier“ For those who are unable to make an appointment for vaccination, please do not worry. After the epidemic situation is controlled, we will resume mass vaccination as soon as possible. For those who have been vaccinated with the first dose, we will sort out the residents with a longer interval of the second dose after resuming the social vaccination with individual appointment, and give priority to the second dose of vaccination. " Zhang zhoubin said.

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